Advia 2120 Hematology Analyzer: Advanced Technology for Accurate CBC Testing

Complete Blood Count (CBC) tests are one of the most frequently ordered lab tests in clinical medicine. For diagnostic labs and hospitals, accurate and efficient CBC testing is essential for diagnosing infections, anemia, blood disorders, and more. The Advia 2120 Hematology Analyzer, developed by Siemens Healthineers, provides a powerful solution to these needs with advanced technology, high throughput, and automated precision.

This article explores how the Advia 2120 delivers reliable CBC and differential results and why it remains a trusted tool in high-volume clinical laboratories.

What Is the Advia 2120?

The Advia 2120 is a fully automated hematology analyzer that uses advanced multi-angle laser flow cytometry and peroxidase staining to deliver highly accurate blood counts. Designed for medium to large laboratories, the system can process up to 120 samples per hour and provide a complete 5-part differential along with comprehensive red and white blood cell indices.

Key Features of the Advia 2120 Hematology Analyzer

1. Advanced Optical and Staining Technology

The Advia 2120 uses a combination of:

• Laser-based flow cytometry for white cell differential
  

• Cytochemical peroxidase staining for improved cell identification
  

• Volume, conductivity, and scatter (VCS) technology for platelet and red cell analysis
  
  

This multi-dimensional approach results in clear separation of cell populations and reduces the need for manual smear reviews.

2. High Throughput for Busy Labs

The analyzer processes up to 120 CBC samples per hour, making it ideal for labs with high daily workloads. It supports continuous sample loading and can prioritize urgent (STAT) samples.

3. Accurate 5-Part Differential

The Advia 2120 delivers a precise 5-part WBC differential, reporting:

• Neutrophils
  

• Lymphocytes
  

• Monocytes
  

• Eosinophils
  

• Basophils
  
  

In addition, it detects and flags abnormal cells for further review.

4. Comprehensive CBC Parameters

The system measures:

• RBC count and indices: MCV, MCH, MCHC, RDW
  

• WBC count and differential
  

• Platelet count and indices: MPV, PDW
  

• Hemoglobin and hematocrit
  

• Reticulocyte count and immature reticulocyte fraction (IRF)
  
  

This allows for broad hematologic evaluation using a single system.

How Advia 2120 Enhances Accuracy

Superior Cell Differentiation

By using flow cytometry with two light angles (forward scatter and side scatter), the Advia 2120 provides precise identification of cell types, including abnormal or immature forms. This is especially important in detecting conditions like

• Leukemia
  

• Aplastic anemia
  

• Thalassemia
  

• Iron deficiency anemia
  
  

Reduced Manual Review

Because of its clear cell separation, the analyzer minimizes false flags and unnecessary slide reviews, saving technician time and improving lab workflow.

Reliable Flagging System

The built-in algorithms automatically flag abnormal or critical results, helping lab professionals quickly identify samples that need further investigation.

Workflow Benefits in the Lab

Seamless Sample Management

• Barcoded sample identification reduces labeling errors
  

• Continuous access carousel allows for walk-away operation
  

• Interfaces with LIS systems for fast data transfer
  
  

Automation Reduces Human Error

• Preloaded reagents with long onboard stability
  

• Auto-cleaning and auto-calibration features
  

• Minimal manual intervention required
  
  

Easy Maintenance

• Simple daily and weekly tasks
  

• Error alerts and diagnostic tools built into the system
  

• Backed by Siemens support and remote monitoring (in some regions)
  
  

Common Applications in Clinical Settings

The Advia 2120 is ideal for:

• General hospital labs performing routine CBCs
  

• Oncology labs monitoring patient blood counts during treatment
  

• Hematology-focused labs needing reticulocyte and immature cell detection
  

• Large outpatient diagnostic labs processing hundreds of samples daily
  
  

Summary: CBC Testing You Can Trust

The Advia 2120 Hematology Analyzer provides advanced CBC and differential testing with a strong combination of speed, accuracy, and automation. With its multi-angle flow cytometry, chemical staining methods, and high throughput, the analyzer supports the high standards demanded by modern clinical labs.

Labs looking to reduce manual review, improve result quality, and boost efficiency will find the Advia 2120 a reliable and cost-effective solution for complete blood count testing.